[Neuroprotective effect of ferulic acid in vitro].

  • Lan Luo, Yue Sun
  • Published 2011 in Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Abstract

OBJECTIVE To investigate the neuroprotective effect of ferulic acid on PC12 cells injuries. METHODS With three models of PC12 cells injured by hypoxia, excitatory amino acids (EAA) and radical, the effect of ferulic acid on injured PC12 cells was observed by MTT assay. RESULTS Compared with three models, ferulic acid (1-100 micromol/L) could promote cell viability notably (P<0.05 or P<0.01). CONCLUSION Ferulic acid has notable protective effect on PC12 cells injured by hypoxia, EAA and radical.

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